It has been believed over the past decade or so that the use of Glucosamine and Chondroitin has benefits for people and indeed pets with osteoarthritis. In 2001 the medical journal, The Lancet, reported “studies had indicated that Glucosamine could dull the pain of arthritis, but experts say the latest study shows for the first time that it could improve the structure of the joints.”
Chondroitin and glucosamine have been recommended in guidelines, prescribed by general practitioners, veterinary surgeons and rheumatologists, and used by patients to ease the symptoms and slow down the progression of osteoarthritis


Glucosamine is an over-the-counter dietary supplement that is a natural, non-toxic compound and safe to use. Some clinical trials have previously shown that it may help to prevent or slow down the loss of joint cartilage. Glucosamine is found naturally in the body and is used in the formation of connective tissue and healthy cartilage. It is made of large protein molecules that act like a sponge to hold water giving connective tissues elasticity and cushioning effects. In certain situations such as increased athletic activity, injuries, arthritis, age and other chronic degeneration our bodies may not be able to keep up with the demand, resulting in cartilage wear and tear. It’s suggested that taking extra glucosamine as a supplement meets this extra requirement. To be effective it must be taken every day. It is a slow acting supplement that may take a month or more to show any effect. Dosage in most studies was 1,500 mg of glucosamine per day. Not cheap!


New research has now been published in the BMJ (British Medical Journal) following a data collection of existing studies, stating that “Chondroitin, glucosamine, and their combination do not have a clinically relevant effect on perceived joint pain or on joint space narrowing”


The report goes on to say ” Some patients, however, are convinced that these preparations are beneficial, which might be because of the natural course of osteoarthritis, regression to the mean, or the placebo effect. We are confident that neither of the preparations is dangerous. Therefore, we see no harm in having patients continue these preparations as long as they perceive a benefit and cover the costs of treatment themselves. Coverage of costs by health authorities or health insurers for these preparations and novel prescriptions to patients who have not received other treatments should be discouraged.”


So, as long you pay for the treatment yourself, they are happy for you to continue wasting your money on expensive supplements which have no physical benefit as long as you feel they are working.


Is this right? I know the placebo effect can be a powerful thing but I would prefer my GP, consultant or vet not to recommend something that has clearly been shown to be ineffective.




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